The development of bispecific Wicker Basket antibodies that bind at least two different targets relies on bringing together multiple binding domains with different binding properties and biophysical characteristics to produce a drug-like therapeutic.These building blocks play an important role in the overall quality of the molecule and can influenc
A new archosauriform species from the Panchet Formation of India and the diversification of Proterosuchidae after the end-Permian mass extinction
Proterosuchidae represents the oldest substantial diversification of Archosauromorpha and plays a key role in understanding the biotic recovery after the end-Permian mass extinction.Proterosuchidae was long treated as a wastebasket taxon, but recent revisions have reduced its taxonomic content to five valid species from the latest Permian of Russia
Mineralogical, textural, structural and geochemical aspects of Nakhlak lead mine, Isfahan
Nakhlak lead mine is located at the Nakhlak mountain 55 km NE of Anarak town in Isfahan province.The mineralogy is simple; galena and barite are the main primary minerals and cerussite is the main secondary mineral.Sphalerite, pyrite, chalcopyrite, tetrahedrite-tennantite and acanthite occur as minor and trace mineral inclusions in galena.Secondary
A snapshot of catastrophic post-disaster health expenses post-Haiyan
Introduction: This paper provides a snapshot of the health-care costs, out-of-pocket expenditures and available safety nets post-Typhoon Haiyan.Methods: This descriptive study used a survey and document review to report direct and indirect PANTIES health-care costs and existing financial protection mechanisms used by households in two municipalitie
Pheromone traps to suppress populations of the smaller European elm bark beetle
Dutch elm disease (DED) has devastated elm populations throughout large portions of the eastern and midwestern United States.This disease has gradually foot adj. spread westward since its accidental introduction from Europe into North America in 1930.First discovered in California in Sonoma County in August, 1975, DED is a threat to elm populations